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Table 5 Absolute and relative organ weight of control and treated mice (male and female) in the acute toxicity study of Berberis aristata diterpenes

From: Scientific validation of the antimicrobial and antiproliferative potential of Berberis aristata DC root bark, its phytoconstituents and their biosafety

Organs Absolute organ weight (g)* Relative organ weight (%)*
Control Treated Control Treated
Male
Liver 0.724 ± 0.031 0.716 ± 0.031 2.453 ± 0.031 2.442 ± 0.030
Kidneys 0.401 ± 0.022 0.392 ± 0.023 1.355 ± 0.035 1.333 ± 0.034
Heart 0.165 ± 0.007 0.160 ± 0.007 0.558 ± 0.007 0.546 ± 0.009
Female
Liver 0.827 ± 0.044 0.813 ± 0.031 2.613 ± 0.055 2.633 ± 0.048
Kidneys 0.410 ± 0.023 0.399 ± 0.016 1.297 ± 0.0353 1.294 ± 0.026
Heart 0.166 ± 0.0118 0.159 ± 0.0062 0.524 ± 0.0195 0.516 ± 0.0104
  1. * Data indicate mean ± SEM (n = 6 for each group). There was no significant difference (p > 0.05) between the test and control groups as indicated by Post hoc Tukey’s t-test