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Table 5 Absolute and relative organ weight of control and treated mice (male and female) in the acute toxicity study of Berberis aristata diterpenes

From: Scientific validation of the antimicrobial and antiproliferative potential of Berberis aristata DC root bark, its phytoconstituents and their biosafety

Organs

Absolute organ weight (g)*

Relative organ weight (%)*

Control

Treated

Control

Treated

Male

Liver

0.724 ± 0.031

0.716 ± 0.031

2.453 ± 0.031

2.442 ± 0.030

Kidneys

0.401 ± 0.022

0.392 ± 0.023

1.355 ± 0.035

1.333 ± 0.034

Heart

0.165 ± 0.007

0.160 ± 0.007

0.558 ± 0.007

0.546 ± 0.009

Female

Liver

0.827 ± 0.044

0.813 ± 0.031

2.613 ± 0.055

2.633 ± 0.048

Kidneys

0.410 ± 0.023

0.399 ± 0.016

1.297 ± 0.0353

1.294 ± 0.026

Heart

0.166 ± 0.0118

0.159 ± 0.0062

0.524 ± 0.0195

0.516 ± 0.0104

  1. * Data indicate mean ± SEM (n = 6 for each group). There was no significant difference (p > 0.05) between the test and control groups as indicated by Post hoc Tukey’s t-test
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