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Table 1 Kinetic parameters of HEK293 E2-CD154 cells growing in different culture media

From: Plasticity of the HEK-293 cells, related to the culture media, as platform to produce a subunit vaccine against classical swine fever virus

Kinetic parameters

Culture media

Pro293SCDM

CDM4HEK293

SFM4HEK293

CPCHO

Xmax (× 106 cell/mL)

0.96 ± 0.098

1.85 ± 0.13

2.68 ± 0.25

3.47 ± 0.53

µmax (× 10−2 h−1)

1.61 ± 0.10

4.41 ± 0.06

3.36 ± 0.04

1.79 ± 0.02

td (h)

62.8 ± 10.8

23.4 ± 5.7

29.8 ± 2.1

58.2 ± 17.0

  1. Each value represents the average from four determinations ± standard deviation
  2. Xmax, maximum cell density; µmax, maximum specific growth rate; td, cell doubling time
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