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Table 1 Related parameters in the scale-up biotransformation process of 5000-L reactor

From: Optimization of whole-cell biotransformation for scale-up production of α-arbutin from hydroquinone by the use of recombinant Escherichia coli

Parameters Batch 1# Batch 2#
Final concentration, mM
α-Arbutin 397 375
Hydroquinone 4.54 6.18
Total yield of α-arbutin, kg ~ 378 ~ 408
Total feeding amount of Hydroquinone, kg 161 175
Total amount of sucrose, kg 1150 1600
Final volume, kL ~ 3.5 ~ 4.0
Catalytic time, h 22 22.5
Productivity, kg·kL−1 h−1 4.91 4.53
Molar conversion rate, % 95% 94.2%