|
Virus
|
No. detected (MNCP/rRT-PCR)a
|
Sensitivity (%) (95% CI)
|
PPVs (%) (95% CI)
|
Overall concordance rate (%) (95% CI)
|
P value (McNemar’s test)
|
|---|
|
+/+
|
+/−
|
−/+
|
−/−
|
|---|
|
Influenza A
|
69
|
5
|
0
|
0
|
100.00 (93.43–100.00)
|
93.24 (84.27–97.49)
|
93.24 (84.27–97.49)
|
0.06
|
|
Influenza B
|
40
|
1
|
1
|
0
|
97.56 (85.60–99.87)
|
97.56 (85.60–99.87)
|
95.24 (82.58–99.17)
|
1.00
|
- +: positive; −: negative; MNCP: micro/nanofluidic chip platform; rRT-PCR: real-time reverse transcription polymerase chain reaction; CI: confidence interval; PPVs: positive predictive values
- aOf 266 samples, 74 and 42 samples had opposite results between MNCP and RIDT for influenza A and B virus detection, respectively
