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Table 6 Samples with opposite results between MNCP and RIDT were further compared with rRT-PCR results

From: Evaluation of a novel micro/nanofluidic chip platform for the detection of influenza A and B virus in patients with influenza-like illness

Virus

No. detected (MNCP/rRT-PCR)a

Sensitivity (%) (95% CI)

PPVs (%) (95% CI)

Overall concordance rate (%) (95% CI)

P value (McNemar’s test)

+/+

+/−

−/+

−/−

Influenza A

69

5

0

0

100.00 (93.43–100.00)

93.24 (84.27–97.49)

93.24 (84.27–97.49)

0.06

Influenza B

40

1

1

0

97.56 (85.60–99.87)

97.56 (85.60–99.87)

95.24 (82.58–99.17)

1.00

  1. +: positive; −: negative; MNCP: micro/nanofluidic chip platform; rRT-PCR: real-time reverse transcription polymerase chain reaction; CI: confidence interval; PPVs: positive predictive values
  2. aOf 266 samples, 74 and 42 samples had opposite results between MNCP and RIDT for influenza A and B virus detection, respectively