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Table 1 Nanoparticles with antibacterial activity and the effects generated on bacterial species

From: Antibacterial potential associated with drug-delivery built TiO2 nanotubes in biomedical implants

Materials or NPs Target bacteria Effects References
TiO2 Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Bacteroides fragilis, Enterococcus hirae, Salmonella Typhimurium, Streptococcus mutans Bactericidal effect after photoactivation of TiO2; membrane disruption; peroxidation of the polyunsaturated phospholipid component of the lipid membrane; loss of respiratory activity; induction of ROS generation; DNA damage and cell death Hajipour et al. (2012), Tsuang et al. (2008), Kumar et al. (2011a, b), Seil and Webster (2012), Cui et al. (2012a, b), Ali et al. (2016)
Ag Bacillus subtilis, Enterobacter sp., Marinobacter sp., Pseudomonas putida, E. coli, Vibrio cholerae, Salmonella Typhi, P. aeruginosa, Acinetobacter baumannii, Clostridium diphtheriae, S. aureus, Streptococcus pyogenes, Staphylococcus epidermidis, Enterococcus faecalis, Klebsiella pneumoniae, Listeria monocytogenes, Proteus mirabilis, Micrococcus luteus, S. mutans Reduction in bacterial growth and viability; electrostatic interactions with bacterial membrane; action on the cellular permeability and respiration; interaction with organelles and biomolecules; ROS generation; modulation of cell signaling; DNA damage Sinha et al. (2011), Jiang et al. (2009), Kumar et al. (2011a, b), Lee et al. (2018), Hajipour et al. (2012), Gajjar et al. (2009), Seil and Webster (2012), Morones et al. (2005), Dakal et al. (2016), Rai et al. (2012), Franci et al. (2015), Nour El Din et al. (2016), Ruparelia et al. (2008), Hemeg (2017), Yoon et al. (2007)
Au S. aureus, E. coli, B. subtilis, K. pneumoniae, P. aeruginosa Inhibition of bacterial growth; change in the membrane potential, reduction of respiratory and ATPase activities, and inhibition of subunit of the ribosome preventing tRNA binding; optical properties; bacterial membrane disruption Shamaila et al. (2016), Cui et al. (2012a, b), Huo et al. (2016), Hemeg (2017)
ZnO Halophilic bacterium, Marinobacter sp., B. subtilis, Enterobacter sp., E. coli, Pseudomonas fluorescens, S. aureus, P. aeruginosa, S. typhimurium, P. putida Inhibition of bacterial growth; change in cell morphology and reduction in cell size; cell membrane disruption and accumulation of nanoparticles in the cytoplasm; electrostatic interactions with bacterial membrane; induction of ROS production, DNA damage and cell death Hajipour et al. (2012), Sinha et al. (2011), Jiang et al. (2009), Kumar et al. (2011a, b), Azam et al. (2012), Gajjar et al. (2009), Feris et al. (2010), Baek and An (2011), Sirelkhatim et al. (2015), Esparza-Gonzalez et al. (2016), Seil and Webster (2012)
Cu B. subtilis, E. coli, P. aeruginosa, S. aureus, P. putida, M. luteus, K. pneumoniae Reduction of bacterial growth; dissipation of cell membrane potential; ROS generation; lipid peroxidation; protein oxidation and DNA degradation Azam et al. (2012), Lee et al. (2018), Gajjar et al. (2009), Chatterjee et al. (2014), Yoon et al. (2007), Ramyadevi et al. (2012), Bogdanovic et al. (2014), Ruparelia et al. (2008), Baek and An (2011)
Se S. aureus, E. coli Reduction of bacterial growth Guisbiers et al. (2016)
SiO2 E. coli, B. subtilis, P. fluorescens Membrane disruption; reduction of bacterial growth Lee et al. (2018), Seil and Webster (2012), Jiang et al. (2009)
NiO Streptococcus pneumoniae, E. coli, B. subtilis, S. aureus, P. aeruginosa Increase of bacterial wall permeability; inhibition of microbial growth associated with intrinsic toxic properties of metal Khashan et al. (2016), Baek and An (2011)
Al2O3 E. coli, B. subtilis, P. fluorescens Reduction of bacterial growth by particle penetration and cell wall damage Lee et al. (2018), Seil and Webster (2012), Hajipour et al. (2012), Jiang et al. (2009), Simon-Deckers et al. (2009), Ansari et al. (2014)
Fe2O3 E. coli, B. subtilis, P. aeruginosa, S. aureus, S. epidermidis Inhibition of bacterial growth Azam et al. (2012), Taylor and Webster (2009), Seil and Webster (2012)
Y2O3 E. coli, S. aureus, P. aeruginosa, Serratia marcescens Inhibition of bacterial growth Kannan and Sundrarajan (2015), Lee et al. (2018)
YF3 E. coli, S. aureus Reduction of bacterial colonization on YF3 coated-surface and antibiofilm activities Lellouche et al. (2012a, b), Hemeg (2017)
CdS E. coli Antibiofilm activity Dhanabalan and Gurunathan (2015), Hemeg (2017)
MgF2 E. coli, S. aureus Inhibition of biofilm formation; ROS generation, lipid peroxidation and penetration of cell envelope Lellouche et al. (2012a, b), Hemeg (2017)
Bi S. mutans Reduction of bacterial growth; inhibition of biofilm formation Hernandez-Delgadillo et al. (2012), Hemeg (2017)
  1. NPs nanoparticles, ROS reactive oxygen species