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Table 1 The degree of the changes in different rat organs after been treated with toxic and non-toxic doses of GNPs in the three tested rat groups

From: Effects of biologically produced gold nanoparticles: toxicity assessment in different rat organs after intraperitoneal injection

Organs and parameters Groups
Control The group which received non toxic dose of GNPs The group which received toxic dose of GNPs
Kidney
 Changes in the glomeruli 0 1 1
 Changes in the Bowman’s capsules 0 0 0
 Changes in the proximal and distal tubules 0 0 0
 Present of the hyperemia and inflammation 0 0 1
Liver
 Changes in the hepatocytes structure 0 1 1
 Changes in the lobular central vein 0 1 0
 Changes in the portal tract 0 0 0
 Changes in the sinusoidal space 0 0 1
Testis
 Changes in the seminiferous tubules 0 0 1
 Changes in the spermatogenic cells 0 0 0
 Changes in the sertoli cells 0 0 0
 Changes in the interstitial tissue and leydig cells 0 0 1
  1. In the table, 0 represented no changes, 1 represented mild changes, 2 represented the middle and 3 represented the maximum changes