In silico analysis as a strategy to identify candidate epitopes with human IgG reactivity to study Porphyromonas gingivalis virulence factors

AMB Express

Table 1 Characteristics of subjects without periodontitis and patients with chronic periodontitis (Brazil, 2018)

Subjects	WP group^a (n = 21)	CP group^a (n = 20)	P-value (≤ 0.05)
Age in years	34.5	33.0	0.89
Median (IQR)	(24.5–41.3)	(24.8–45.0)	0.89
Sex proportion	18/3	14/6	0.28
(female/male)
Number of teeth	25.0	26.0	0.39
Median (IQR)	(20.5–27.0)	(20.3–28.0)	0.39
%BOP	11.0	44.6	0.00
Median (IQR)	(4.9–22.9)	(28.4–59.4)	0.00
%CAL ≥ 3 mm	1.2	26.8	0.00
Median (IQR)	(0.0–14.8)	(8.8–45.5)	0.00
%CAL ≥ 5 mm	0.0	11.5	0.00
Median (IQR)	(0.0–0.0)	(3.5–29.1)	0.00
%PD ≥ 4 mm	0.0	15.3	0.00
Median (IQR)	(0.0–2.7)	(8.3–27.3)	0.00

Third molars were excluded
Mann–Whitney U test and Fisher’s exact test
CP: chronic periodontitis; WP: without periodontitis; BOP: bleeding on probing; CAL: clinical attachment level; PD: probing depth; IQR: interquartile range
^aClassification according to Gomes-Filho et al. (2007)