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Table 2 Experimental design for media optimization

From: Enhancement of ascomycin production via a combination of atmospheric and room temperature plasma mutagenesis in Streptomyces hygroscopicus and medium optimization

Run A B C Ascomycin (mg/L)
1 − 1 0 − 1 852.1
2 − 1 1 0 899.4
3 0 − 1 − 1 954
4 − 1 0 1 1162.6
5 0 0 0 1435.8
6 1 0 − 1 1054.9
7 0 0 0 1397.5
8 1 0 1 1123.1
9 0 1 − 1 703.5
10 1 1 0 758.2
11 1 − 1 0 1228.4
12 0 − 1 1 1094.4
13 0 0 0 1416.2
14 0 1 1 855.1
15 0 0 0 1458.2
16 0 0 0 1408.8
17 − 1 − 1 0 1089.8