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AMB Express
Fig. 1 | AMB Express

Fig. 1

From: Enhancement of ascomycin production via a combination of atmospheric and room temperature plasma mutagenesis in Streptomyces hygroscopicus and medium optimization

Fig. 1

ARTP mutagenesis breeding for S. hygroscopicus ATCC 14891 strain. a The experimental procedure of high-yield strain screening by ARTP breeding system. b Lethality rate and positive mutation rate of ATCC 14891 strain after ARTP mutagenesis. c Ascomycin production of the isolated mutants after ARTP mutagenesis (the black solid line represented 373.8 mg/L—the production of original ATCC 14891 strain, while the red dotted line was for the yield of positive mutant strains, in which ascomycin production was found to be over 10% higher relative to ATCC 14891 strain). d The comparison of ascomycin production between SFK-36 and ATCC 14891 in shake flask. e Genetic stability of SFK-36 in ascomycin production by natural subculture

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