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Table 1 Representative DAHPSs from different types of microorganisms

From: Isolation and biochemical characterization of a metagenome-derived 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase gene from subtropical marine mangrove wetland sediments

Protein Organism T Feedback structure Feedback inhibitor PF References
AroG, AroF, AroH Escherichia coli Iα N-Region Phe, Tyr, Trp 2, 4 Ray and Bauerle (1991); Schoner and Herrmann (1976); Shumilin et al. (1999, 2004)
Aro3, Aro4 Saccharomyces cerevisiae Iα N-Region Phe, Tyr, Trp 2, 4, 8 Helmstaedt et al. (2005); König et al. (2004); Künzler et al. (1992); Teshiba et al. (1986)
Nme DS Neisseria meningitidis Iα N-Region Phe, Tyr, Trp 4 Cross et al. (2013); Heyes et al. (2014)
DAHPPae Pseudomonas aeruginosa Iα Sterritt et al. (2018)
Tm DS Thermotoga maritima Iβ N-Ferredoxin-like domain Phe, Tyr 2, 4 Shumilin et al. (2004); Wu et al. (2003)
Pfu DS Pyrococcus furiosus Iβ None None of Phe, Tyr, and Trp 2, 4 Schofield et al. (2004, 2005)
Gsp DS Geobacillus sp. Iβ N-Chorismate mutase Prephenate 4 Nazmi et al. (2016)
Ap DS Aeropyrum pernix Iβ None None of Phe, Tyr, Trp, chorismate, shikimate, and prephenate, 4 Zhou et al. (2012)
aroA(Q)168 Bacillus subtilis Iβ N-Chorismate mutase Chorismate, Prephenate 4 Wu et al. (2005)
Pg DS Porphyromonas gingivalis Iβ C-Chorismate mutase Chorismate, prephenate   Wu and Woodard (2006)
Lm DS Listeria monocytogenes Iβ N-Chorismate mutase Chorismate, prephenate 4 Light et al. (2012)
Pae DAHPSPA2843 Pseudomonas aeruginosa II N-Region Trp 4 Sterritt et al. (2018)
Mt DAHPS Mycobacterium tuberculosis II N-Chorismate mutase Phe/Tyr, Phe/Trp, Tyr/Trp, Tyr, Trp, and chorismate 2, 4 Light et al. (2012); Webby et al. (2010)
AroG, AroF, AroH Corynebacterium glutamicum II N-Region Phe, Tyr, Trp 2, 4 Burschowsky et al. (2018); Liu et al. (2008)
Hpy DS Helicobacter pylori II Unknown None of Phe, Tyr, Trp, and chorismate 2 Webby et al. (2005b)
  1. T DAHPS type, PF polymer form