TY - JOUR AU - Mamarabadi, Mojtaba AU - Tanhaeian, Abbas AU - Ramezany, Younes PY - 2018 DA - 2018/11/02 TI - Antifungal activity of recombinant thanatin in comparison with two plant extracts and a chemical mixture to control fungal plant pathogens JO - AMB Express SP - 180 VL - 8 IS - 1 AB - The most common method for controlling plant diseases is the application of chemical pesticides and sometimes use of resistant cultivars. Due to the effects of chemical pesticides on human and environmental health, mutation in pathogens and resistance to various toxins besides the challenges with resistant cultivar production, the constant use of these methods are not recommended any longer. Thus, use of biological control agents along with the natural ingredient extracted from plants and application of peptide with antimicrobial activity, have been the focus of many researchers. In the present study, the antifungal activity of two plant extracts named Turmeric and Persian lilac in comparison with a chemical mixture and recombinant thanatin were evaluated against five following fungal plant pathogens; Geotrichum candidum, Botrytis cinerea, Rhizoctonia solani, Alternaria tenuissima and Gibberella fujikuroi. The results showed that, all treatments have antifungal activity against tested fungi. Both plant extracts were shown an acceptable antifungal activity against tested fungi but their inhibition effects was not comparable with chemical mixture. Turmeric showed a higher rate of mycelial inhibition than Persian lilac. Amongst all treatment, thanatin showed a great antifungal activity by its application at µg level under both in vitro and in vivo condition. Considering to the compatibility of thanatin with human health and environmental safety we could imagine a clear perspective for the application of this recombinant peptide in sustainable agriculture. SN - 2191-0855 UR - https://doi.org/10.1186/s13568-018-0710-4 DO - 10.1186/s13568-018-0710-4 ID - Mamarabadi2018 ER -