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Fig. 9 | AMB Express

Fig. 9

From: Potential of Bacillus subtilis lipopeptides in anti-cancer I: induction of apoptosis and paraptosis and inhibition of autophagy in K562 cells

Fig. 9

TEM photo of lipopeptide-treated K562 cells and the western blot analysis of the expression of apoptosis-related proteins. a TEM photo of lipopeptide-treated K562 cells. Arrow 1 shows the apoptotic body; arrow 2 indicates the autophagosome; and arrow 3 indicates the cytoplasmic vacuoles, typical markers of paraptosis. The scale bar is 2 μm. b TEM photo of K562 cells treated with lipopeptides together with caspase inhibitors. The black arrows mark the mitochondrion swelling, and the red arrows mark the ER swelling; the scale bar is 2 μm. c The expression of key proteins related to autophagy and paraptosis. d Quantitative analysis of the levels of gene expression shown in c

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