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Table 1 Research progress on the biotransformation of decane and methyl decanoate to sebacic acid

From: Effect of decanoic acid and 10-hydroxydecanoic acid on the biotransformation of methyl decanoate to sebacic acid

Microorganisms Substrates Titer (g/L) Productivity (g/L · h) References
C. cloacae 310 Decane 0.427 a Shiio and Uchio (1971)
Engineered C. tropicalis Decane 0.94 a Chung et al. (2015), Beardslee et al. (2014)
Engineered C. tropicalis Decane + methyl decanoate ± 13b a Beardslee et al. (2014)
C. tropicalis mutant Decane + methyl decanoate 27.0 ± 2.14c 0.50 ± 0.04 This study
C. tropicalis mutant Decane + methyl decanoate 34.5 ± 1.10d 0.64 ± 0.02 This study
  1. a Not enough information
  2. b Decane induction by single bolus addition of 10 g/L decane (induction time: 6 h)
  3. c Decane induction by single bolus addition of 1% v/v decane (induction time: 10 h)
  4. d Decane induction by substrate limitation condition/continuous feeding (0.65 g/L/h decane for 10 h)