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Table 2 Activities of nine antibiotics against bacterial isolates harvested from stepwise increased STM exposures

From: Culture-based study on the development of antibiotic resistance in a biological wastewater system treating stepwise increasing doses of streptomycin

Antibiotics Antibiotic range (µg mL−1) Prevalence of antibiotic resistance (%)a
0 mg L−1, STM 0.1 mg L−1, STM 1 mg L−1, STM 5 mg L−1, STM 25 mg L−1, STM 50 mg L−1, STM
AZ 0.016–256 0 38.4 38.4 30.8 23.0 23.0
TZ 0.016–256 7.7 23.0 38.4 23.0 15.4 15.4
EF 0.002–32 0 0 0 0 0 0
ETP 0.064–1024 0 0 7.7 7.7 7.7 7.7
SX 0.002–32 7.7 15.4 30.8 30.8 23.0 0
TC 0.016–256 0 23.0 30.8 30.8 30.8 15.4
TGC 0.016–256 0 0 0 0 0 0
TM 0.016–256 7.7 7.7 7.7 15.4 15.4 30.8
Sm 1–1024 15.4 53.8 69.2 69.2 53.8 53.8
  1. AZ azithromycin, TZ ceftazidime, EF enrofloxacin, ETP ertapenem, SX sulfamethoxazole, TC tetracycline, TGC tigecycline, TM tobramycin, STM streptomycin
  2. aA total of 40 different bacterial strains (78 bacterial isolates, i.e. 13 isolates from each Sm stage) were used for MIC assay and the percentage of antibacterial resistance was calculated by the number of resistant strains among the total stains