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Table 2 Cytotoxic activities of fractions from the crude extracts

From: Microbial diversity of saline environments: searching for cytotoxic activities

Strain ID Crude extract/fraction Extraction solvent Cytotoxic activity of fractions IC50 (µg mL−1)
Cellular line
4T1 MCF7
CG 35 Crude extract Chloroform 117.8 188.6
F 2.1 Hexane:ethyl acetate
8:2
73.8 87.9
F 2.2 Hexane:ethyl acetate
8:2
69.6 68.4
F 4.1 Ethyl acetate 88.2 247.2
F 5.2 Ethyl acetate:methanol
9:1
84.5 79.7
F 5.3 Ethyl acetate:methanol
9:1
72.6 96.3
CG 24 Crude extract Ethyl acetate > 250 57.2
F 6.2 Methanol > 250 138.6
CG 22 Crude extract Chloroform 29.8 76.5
F 6.1 Methanol > 250 44.8
CG 63 Crude extract Chloroform 107 76.4
F 4.1 Ethyl acetate ND 44.4
CG 50 Crude extract Chloroform 158.6 115
F 6.1 Methanol 31.2 > 250
USBA 344 Crude extract Ethyl acetate 15 22
F 3.2 Hexane:ethyl acetate
1:1
229.2 80.3
USBA 371 Crude extract Chloroform 5.5 4.5
F 4.1 Ethyl acetate 15.2 26.6
F 4.2 Ethyl acetate:methanol
9:1
8.9 16.3
F 5.1 Ethyl acetate:methanol
9:1
7.2 14.5
F 6.1 Methanol 28.7 49.0
  1. ND No data