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Table 5 Effect of feeding rate on growth of P. acidilactici in constant fed-batch fermentation using 2 L stirred tank bioreactor

From: Strategies for improving production performance of probiotic Pediococcus acidilactici viable cell by overcoming lactic acid inhibition

Kinetic parameter

Feeding rate (L/h)

0.008

0.015

0.03

Maximum viable cell concentration (cfu/mL)

1.9 × 1012 ± 0.21b

1.1 × 1013 ± 0.14a

1.6 × 1012 ± 0.12c

Time to reach maximum viable cell concentration (h)

12b

14a

14a

Viable cell yield (cfu/gGlucose)

2.1 × 1014 ± 0.16b

1.2 × 1015 ± 0.11a

1.8 × 1014 ± 0.13c

Viable cell productivity (cfu/mL h)

1.1 × 1010 ± 0.18c

7.9 × 1011 ± 0.12a

1.1 × 1011 ± 0.17b

Maximum lactic acid concentration (g/L)

9.81 ± 0.12a

8.12 ± 0.11c

9.25 ± 0.14b

Lactic acid yield (g/gGlucose)

1.09 ± 0.08a

0.89 ± 0.06b

1.05 ± 0.06a

Lactic acid productivity (g/L h)

0.26 ± 0.11b

0.28 ± 0.08b

0.36 ± 0.07a

  1. The results presented are the average of triplicate experiments and are expressed as mean ± standard deviation
  2. a,b,cMean values in the same row with different superscripts are significantly different from each other (P < 0.05)