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Table 5 Effect of feeding rate on growth of P. acidilactici in constant fed-batch fermentation using 2 L stirred tank bioreactor

From: Strategies for improving production performance of probiotic Pediococcus acidilactici viable cell by overcoming lactic acid inhibition

Kinetic parameter Feeding rate (L/h)
0.008 0.015 0.03
Maximum viable cell concentration (cfu/mL) 1.9 × 1012 ± 0.21b 1.1 × 1013 ± 0.14a 1.6 × 1012 ± 0.12c
Time to reach maximum viable cell concentration (h) 12b 14a 14a
Viable cell yield (cfu/gGlucose) 2.1 × 1014 ± 0.16b 1.2 × 1015 ± 0.11a 1.8 × 1014 ± 0.13c
Viable cell productivity (cfu/mL h) 1.1 × 1010 ± 0.18c 7.9 × 1011 ± 0.12a 1.1 × 1011 ± 0.17b
Maximum lactic acid concentration (g/L) 9.81 ± 0.12a 8.12 ± 0.11c 9.25 ± 0.14b
Lactic acid yield (g/gGlucose) 1.09 ± 0.08a 0.89 ± 0.06b 1.05 ± 0.06a
Lactic acid productivity (g/L h) 0.26 ± 0.11b 0.28 ± 0.08b 0.36 ± 0.07a
  1. The results presented are the average of triplicate experiments and are expressed as mean ± standard deviation
  2. a,b,cMean values in the same row with different superscripts are significantly different from each other (P < 0.05)