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Fig. 8 | AMB Express

Fig. 8

From: Production of bioactive liver-targeting interferon Mu-IFN-CSP by soluble prokaryotic expression

Fig. 8

Effect of IFN-CSP or mu-IFN-CSP on HBV antigens secretion and HBV-DNA replication in HepG2.2.15 cells. HepG2.2.15 cells were cultured in the presence of IFN-CSP or mu-IFN-CSP for 6 days. Hepatitis B surface antigen (HBsAg; a) and hepatitis B e antigen (HBeAg; b) in the culture supernatants were analyzed by enzyme-linked immunosorbant assay (ELISA). Supernatant HBV-DNA (c) and intracellular HBV-DNA (d) were measured by real-time quantitative PCR. Data represent the mean ± SEM of three experiments. ***P < 0.001 drug group vs control group; # P < 0.05, ## P < 0.01 IFN-CSP group vs mu-IFN-CSP group

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