Skip to main content

Table 1 Summary of water solubility and pharmacological properties of (−)-menthol β-d-glucoside and (−)-menthol

From: Improvement of the pharmacological activity of menthol via enzymatic β-anomer-selective glycosylation

 

Water solubility (g/L)

Flavor

The threshold concentration for cooling (%)

Expression of activation marker on THP-1 cells

Irritating sensation to the skin

CD54

CD86

Menthol

NT

Yes

0.125

Positive

Negative

Yes

Menthol β-glucoside

18.1

No

0.06

Negative

Negative

No

Controla

0.66

NT

NT

NT

NT

NT

  1. NT not tested
  2. aControl for water solubility were menthol α-glucoside