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Table 4 Minimum inhibitory concentration (MIC) of organic extract and phytoconstituents isolated from Gymnema sylvestre leaves

From: In vitro antimicrobial potential of extracts and phytoconstituents from Gymnema sylvestre R.Br. leaves and their biosafety evaluation

Orgd

MIC (mg/ml)

Aqa

EAb

Flavonoids

Cardiac glycosides

Saponins

Diterpenes

Gentamicin

Chloramphenicol

SA

2.5

0.5

ND

3

ND

0.7

0.0002

0.01

SE

ND

0.7

3

5

5

ND

0.01

0.01

EC

2.5

0.5

3

3

3

ND

0.005

0.01

EF

ND

0.7

5

3

ND

ND

0.03

0.3

KP1

1

0.5

0.1

0.7

0.5

0.5

0.0002

0.01

KP2

ND

0.5

1

5

10

1

0.0005

0.001

SF

2.5

0.5

3

3

ND

3

0.005

0.01

ST1

3

0.5

ND

5

ND

ND

0.005

0.1

ST2

2.5

0.5

3

1

5

5

0.0003

0.001

PA

1

0.1

0.7

5

5

1

0.005

0.7

CA

3

0.1

1

3

1

ND

0.0003c

ND

CT

ND

1

ND

ND

ND

ND

0.1c

ND

MRSA

3

0.5

0.1

1

5

0.7

0.005

0.01

  1. ND not determined
  2. aAqueous extract
  3. bEthyl acetate extract
  4. cAmphotericin B
  5. d Organisms SA, Staphylococcus aureus; SE, Staphylococcus epidermidis; EC, Escherichia coli; KP1, Klebsiella pneumoniae 1; KP2, Klebsiella pneumoniae 2; SF, Shigella flexneri; ST1, Salmonella typhimurium 1; ST2, Salmonella typhimurium 2; PA, Pseudomonas aeruginosa; CA, Candida albicans; CT, Candida tropicalis; MRSA, Methicillin-resistant Staphylococcus aureus