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Table 4 Minimum inhibitory concentration (MIC) of organic extract and phytoconstituents isolated from Gymnema sylvestre leaves

From: In vitro antimicrobial potential of extracts and phytoconstituents from Gymnema sylvestre R.Br. leaves and their biosafety evaluation

Orgd MIC (mg/ml)
Aqa EAb Flavonoids Cardiac glycosides Saponins Diterpenes Gentamicin Chloramphenicol
SA 2.5 0.5 ND 3 ND 0.7 0.0002 0.01
SE ND 0.7 3 5 5 ND 0.01 0.01
EC 2.5 0.5 3 3 3 ND 0.005 0.01
EF ND 0.7 5 3 ND ND 0.03 0.3
KP1 1 0.5 0.1 0.7 0.5 0.5 0.0002 0.01
KP2 ND 0.5 1 5 10 1 0.0005 0.001
SF 2.5 0.5 3 3 ND 3 0.005 0.01
ST1 3 0.5 ND 5 ND ND 0.005 0.1
ST2 2.5 0.5 3 1 5 5 0.0003 0.001
PA 1 0.1 0.7 5 5 1 0.005 0.7
CA 3 0.1 1 3 1 ND 0.0003c ND
CT ND 1 ND ND ND ND 0.1c ND
MRSA 3 0.5 0.1 1 5 0.7 0.005 0.01
  1. ND not determined
  2. aAqueous extract
  3. bEthyl acetate extract
  4. cAmphotericin B
  5. d Organisms SA, Staphylococcus aureus; SE, Staphylococcus epidermidis; EC, Escherichia coli; KP1, Klebsiella pneumoniae 1; KP2, Klebsiella pneumoniae 2; SF, Shigella flexneri; ST1, Salmonella typhimurium 1; ST2, Salmonella typhimurium 2; PA, Pseudomonas aeruginosa; CA, Candida albicans; CT, Candida tropicalis; MRSA, Methicillin-resistant Staphylococcus aureus