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Table 3 Antimicrobial activity of phytoconstituents isolated from Gymnema sylvestre leaves

From: In vitro antimicrobial potential of extracts and phytoconstituents from Gymnema sylvestre R.Br. leaves and their biosafety evaluation

Orgc Alkaloids Flavonoids Saponins C. glycosides Diterpenes Phytosterols Gentamicin Chloramphenicol
Average zone of inhibition (mm)b
 SA 14.66 ± 0.33 0 0 15.33 ± 0.66 16 ± 0 14 ± 0 34.5 ± 0.50 26 ± 1.00
 SE 14.33 ± 0.33 17.33 ± 0.33 15 ± 0 19.66 ± 0.33 0 13.33 ± 0.33 26.5 ± 0.50 28.5 ± 0.50
 EC 0 15 ± 0.57 15.33 ± 0.33 15.66 ± 0.33 13.66 ± 0.33 0 31 ± 1.00 25 ± 0
 EF 0 19.66 ± 0.66 0 19.33 ± 0.33 0 0 27.5 ± 0.50 26.5 ± 0.50
 KP1 15.33 ± 0.33 19.66 ± 0.33 24.33 ± 0.33 16.66 ± 0.33 15.66 ± 0.33 13.66 ± 0.33 40.5 ± 0.50 38 ± 1.00
 KP2 19.66 ± 0.33 23 ± 0.57 17.33 ± 0.33 16.66 ± 0.66 14 ± 0 15 ± 0 37.5 ± 1.50 26.5 ± 0.50
 SF 0 13.33 ± 0.66 0 14.33 ± 0.33 13.33 ± 0.33 0 30.5 ± 0.50 27.5 ± 0.50
 ST1 0 0 0 13 ± 0 12.66 ± 0.33 0 35 ± 0 23 ± 0
 ST2 15 ± 0 20.33 ± 0.88 13.66 ± 0.33 17 ± 0 13 ± 0 0 43 ± 1.00 40.5 ± 0.50
 PA 0 17 ± 0 20 ± 0.57 14.66 ± 0.33 13.33 ± 0.33 0 40.5 ± 0.50 28.5 ± 0.50
 CA 19.66 ± 0.33 35 ± 0 19.66 ± 0.33 20.33 ± 0.88 0 17.33 ± 0.33 36.5 ± 0.50a ND
 CT 0 0 0 0 0 0 27.5 ± 0. 50a ND
 MRSA 13.66 ± 0.33 19 ± 0 18.33 ± 0.33 17.66 ± 0.33 15 ± 0 0 42 ± 0 39.5 ± 0.50
  1. ND not done
  2. aAmphotericin B
  3. bValues are expressed as Mean ± SEM for N = 3
  4. c Organisms SA, Staphylococcus aureus; SE, Staphylococcus epidermidis; EC, Escherichia coli; KP1, Klebsiella pneumoniae 1; KP2, Klebsiella pneumoniae 2; SF, Shigella flexneri; ST1, Salmonella typhimurium 1; ST2, Salmonella typhimurium 2; PA, Pseudomonas aeruginosa; CA, Candida albicans; CT, Candida tropicalis; MRSA, Methicillin-resistant Staphylococcus aureus