Table 1 The genetic information of the bacteria used in the present study
Strain name | GCSC number | Deleted gene | Mutation function |
|---|---|---|---|
BW25113 | 7636 | None | Not applicable |
JW5437-1 | 11,387 | rpoS | Master regulator of the general stress response in E. coli. In addition, rpoS transcribes a significant fraction of genes related to sugar and polyamine metabolism in response to cellular stresses and in nucleic acid synthesis and modification (Eisenstark et al. 1996) |
JW3933-3 | 12,039 | oxyR | “Oxidative stress regulator,” is the transcriptional dual regulator for the expression of antioxidant genes in response to oxidative stress, in particular, elevated levels of hydrogen peroxide (Kullik et al. 1995) |
JW4024-1 | 10,892 | soxR | “Superoxide response protein,” is negatively autoregulated and controls the transcription of the regulon involved in defense against redox-cycling drugs (Demple 1996) |