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Table 1 Levels and codes of variables used for CCD

From: Carboxymethyl cellulase production optimization from newly isolated thermophilic Bacillus subtilis K-18 for saccharification using response surface methodology

Parameter

Code

Levels

−2

−1

0

+1

+2

Substrate conc. (%)

X1

0.5

1.0

1.5

2.0

2.5

Inoculum size (%)

X2

1

2

3

4

5

Yeast extract (%)

X3

0.2

0.6

0.8

1.0

1.2

pH

X4

4.5

5

5.5

6

6.5

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