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Table 4 Experimental design by using CCD, experimental value and predicted value

From: Optimization of medium compositions to improve a novel glycoprotein production by Streptomyces kanasenisi ZX01

Run x 1 x 2 x 3 Experimental value (µg/L) Predicted value (µg/L) Residual
1 −1 1 1 482.32 483.16 −0.84
2 0 0 0 536.84 539.66 −2.82
3 0 0 0 534.15 539.66 −5.51
4 −1 −1 1 397.65 407.10 −9.45
5 0 0 0 545.20 539.66 5.54
6 1 −1 −1 500.43 507.12 −6.69
7 −1 1 −1 438.56 450.54 −11.98
8 0 −1.682 0 465.94 459.06 6.88
9 0 0 0 532.35 539.66 −7.31
10 0 0 0 538.06 539.66 −1.60
11 −1 −1 −1 411.17 417.12 −5.95
12 0 1.682 0 445.41 541.61 3.80
13 0 0 −1.682 486.10 476.23 9.87
14 1 −1 1 529.24 524.82 4.42
15 0 0 0 549.52 539.66 9.86
16 1.682 0 0 556.87 559.33 −2.46
17 −1.682 0 0 407.31 394.15 13.16
18 1 1 −1 531.13 529.22 1.19
19 1 1 1 587.96 589.56 −1.60
20 0 0 1.682 519.37 518.55 0.82