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Table 3 Comparison of Daptomycin production by free and immobilized cells of S. roseosporus

From: Improved production of Daptomycin in an airlift bioreactor by morphologically modified and immobilized cells of Streptomyces roseosporus

Carrier material

Daptomycin conc. (mg/l)

(after first batch)

Daptomycin conc. (mg/l)

(after final batch)

Reusability up to (cycles)

Pellets

810

1430

2

Free cells

750

750

Nil

Refractory brick

700

4895

8

Silk sachets

620

3623

6