Pyruvate production using engineered Escherichia coli

AMB Express

Table 1 Comparison of the pyruvate productivities of E. coli strains

Strain	Genotype	Carbon source	Concentrations (g L⁻¹)	Productivity (g L⁻¹ h⁻¹)	Yield^a (%)	References
E. coli LAFCPCPt-accBC-aceE	MG(1655) ΔldhA ΔadhE ΔpflB Δpta-ackA ΔpoxB Δcra Ptet-accBC Ptet-aceE	Glucose	4.2^b	0.0584	10.6	This study
E. coli LAFCPCPt-accBC-aceE	MG(1655) ΔldhA ΔadhE ΔpflB Δpta-ackA ΔpoxB Δcra Ptet-accBC Ptet-aceE	Glucose	26.1^c	0.363	55.6	This study
E. coli CGSG (6162)	F⁺ aceF10 fadR200 tyrT58(AS) adhE80 mel-1	Glucose, acetate	37.0	1.03	ND	Tomar et al. (2003)
E. coli CGSG (7916)	CGSC(6162) ppc::Kan	Glucose, acetate	35.0	0.972	ND	Tomar et al. (2003)
E. coli TC44	W(3110) (Succ⁺), ΔfocA-pflB::FRT ΔfrdBC ΔldhA Δatp(FH)::FRT ΔadhE::FRT ΔsucA::FRT ΔpoxB::FRT ΔackA::FRT	Glucose	52.0	1.21	77.9	Causey et al. (2004)
E. coli W(1485)lip2	W(1485) F⁺ λ⁻ lipA2	Glucose	25.5	0.797	52.2	Yokota et al. (1994)
E. coli TBLA-1	W(1485)lip2 bgl ⁺ atpA401	Glucose	31.5	0.984	64.4	Yokota et al. (1994)
E. coli YYC202	Hfr zbi::Tn10 poxB1 Δ(aceEF) rpsL pps-4 pfl-1	Glucose, acetate	62.0	1.75	ND	Zelić et al. (2003)
E. coli ALS929	YYC202 ldhA::Kan	Glucose, acetate	70.0	2.06	ND	Zhu et al. (2008)
E. coli ALS(1059)	YYC202 ldhA::Kan arcA726::FRT atpFH::Cam	Glucose, acetate	90	2.05	ND	Zhu et al. (2008)

ND not described
^aYield was the theoretical maximum value
^bPyruvate was produced from N5G medium under standard culture conditions for 72 h
^cPyruvate was produced from N5G medium under optimized culture conditions for 72 h