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AMB Express
Fig. 1 | AMB Express

Fig. 1

From: Angiogenic inhibitors delivered by the type III secretion system of tumor-targeting Salmonella typhimurium safely shrink tumors in mice

Fig. 1

Generation of a tumor-targeting Salmonella strain ST8 for delivery and expression of multiple therapeutic factors. a Schematic diagram of the creation process of strain ST8. b CFU tests of ST8/pcDNA-infA inside tumors of nude mice following intravenous injection. Tumors were collected at 7 and 20 days after bacterial infection, homogenized in PBS and plated onto agar plates with or without ampicillin selection to determine the counts of recombinant and total bacteria, respectively. Values are expressed as mean ± SD, n = 5. c SL7207/pcDNA-infA infected tumors were homogenized and analyzed for the total bacterial number and total bacteria with the plasmids. ND stands for CFU = 0. Shown is the mean CFU per gram tissues plus SD

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