Table 2 Analysis of the conservation in Bcc and predicted immunogenicity of B. cenocepacia J2315 OmpA-like proteins (PF00691)
Protein | Domainsa | MWb | Signal sequencec | Conservationd | B cell epitopes average (predicted peptides)e |
|---|---|---|---|---|---|
BCAL0349 | BON (PF04972) | 32.8 | 1–36 (SPI) | >84 % in Bcc | 0.498 (13) |
OmpA (PF00691) | >72 % in Burkholderia genera | ||||
<66 % with other bacteria | |||||
BCAL2645 | Gly-zipper YMGG (PF13441) | 21.6 | 1–21 (SPII) | >94 % in Bcc | 0.433 (11) |
OmpA (PF00691) | >71 % in Burkholderia genera | ||||
<60 % with other bacteria | |||||
BCAL2958 | OmpA (PF00691) | 23.9 | 1–22 (SPI) | >96 % in Bcc | 0.362 (11) |
>87 % in Burkholderia genera | |||||
<77 % with other bacteria | |||||
BCAL3204 | OmpA (PF00691) | 18.7 | 1–20 (SPII) | >91 % in Bcc | 0.336 (9) |
>82 % in Burkholderia genera | |||||
<70 % with other bacteria | |||||
BCAM0220 | OmpA (PF00691) | 25.3 | 1–22 (SPII) | Not conserved | 0.369 (12) |
BCAM0690 | OmpA (PF00691) | 22.6 | NP | >92 % in Bcc | 0.083 (11) |
>74 % in Burkholderia genera | |||||
<84 % with other bacteria | |||||
BCAM1550 | OmpA (PF00691) | 17.7 | 1–18 (SPII) | Not conserved | 0.319 (10) |
BCAM2255 | OmpA (PF00691) | 18.3 | 1–26 (SPII) | Not conserved | 0.120 (5) |
BCAM2419 | OmpA (PF00691) | 22.9 | 1–17 (SPII) | >74 % in Bcc | 0.363 (12) |
>35 % in Burkholderia genera | |||||
<36 % with other bacteria | |||||
BCAS0237 | OmpA (PF00691) | 23.1 | 1–17 (SPII) | Not conserved | 0.382 (13) |