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Table 1 Fermentation profiles of high-SAM-producing (Kyokai 6) and laboratory (S288C) strains in the presence of glucose with or without l-methionine

From: Metabolome analysis of Saccharomyces cerevisiae and optimization of culture medium for S-adenosyl-l-methionine production

Strain

Kyokai 6

S288C

l-Methionine

+

+

SAM production (mg L−1)

7.5 ± 0.4

177.6 ± 4.0

6.3 ± 0.1

62.6 ± 0.9

Biomass (g CDW L−1)

6.7 ± 0.04

5.6 ± 0.06

5.5 ± 0.05

5.0 ± 0.05

SAM content (mg g CDW−1)

1.1 ± 0.01

31.8 ± 1.0

1.1 ± 0.01

12.5 ± 0.2

Ethanol (g L−1)

17.8 ± 0.5

20.0 ± 0.1

19.5 ± 0.2

20.7 ± 0.1

pH

5.7 ± 0.02

5.3 ± 0.05

6.0 ± 0.03

5.4 ± 0.03

  1. All data were obtained from the averages of three independent experiments ± SD