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Fig. 5 | AMB Express

Fig. 5

From: Metabolome analysis of Saccharomyces cerevisiae and optimization of culture medium for S-adenosyl-l-methionine production

Fig. 5

SAM production mechanism of high-SAM-producing strain estimated in this study. a Without methionine. b With methionine. c With methionine and without yeast extract. The dotted gray arrows represent respiration. The metabolome analysis results revealed that the rate-limiting step for SAM production without and with methionine was methionine and ATP supply, respectively (gray characters). Higher SAM production without yeast extract was explained by enhanced ATP supply with inhibited cell growth

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