Table 2 Cross comparison of up- and down-regulated proteins in specific COG classes in C. necator H16 cultured with different substrates at 24 h pi
COG | Description# | GB-24 vs R80-24 | GB-24 vs FFA-24 | FFA-24 vs R80-24 | |||
|---|---|---|---|---|---|---|---|
Up | Down | Up | Down | Up | Down | ||
C | Energy production | 9 | 11 | 4 | 10 | 6 | 10 |
D | Cell cycle control | 0 | 0 | 0 | 0 | 0 | 0 |
E | Amino acid transport and metabolism | 8 | 6 | 9 | 8 | 0 | 0 |
F | Nucleotide transport and metabolism | 0 | 0 | 0 | 0 | 0 | 0 |
G | Carbohydrate transport and metabolism | 0 | 3 | 1 | 2 | 2 | 1 |
H | Coenzyme transport and metabolism | 4 | 1 | 0 | 0 | 0 | 0 |
I | Lipid transport and metabolism | 6 | 2 | 5 | 9 | 8 | 1 |
J | Translation, ribosomal structure and biogenesis | 2 | 1 | 2 | 1 | 0 | 0 |
K | Transcription | 1 | 2 | 2 | 1 | 0 | 2 |
L | Replication, recombination and repair | 0 | 0 | 2 | 0 | 0 | 0 |
M | Cell wall/membrane envelope biogenesis | 0 | 0 | 7 | 1 | 4 | 0 |
N | Cell motility | 1 | 2 | 1 | 2 | 0 | 0 |
O | Post translational modification, protein turn over, chaperone | 0 | 10 | 1 | 3 | 1 | 8 |
P | Inorganic ion transport and metabolism | 6 | 1 | 0 | 0 | 3 | 0 |
Q | Secondary metabolites biosynthesis, transport and catabolism | 1 | 0 | 2 | 4 | 0 | 0 |
R | General function prediction only | 2 | 3 | 2 | 10 | 5 | 3 |
S | Function unknown | 4 | 5 | 0 | 0 | 2 | 1 |
T | Signal transduction mechanism | 0 | 0 | 1 | 3 | 0 | 0 |
U | Intracellular trafficking, secretion and vesicular transport | 1 | 2 | 0 | 5 | 0 | 3 |
V | Defense mechanism | 0 | 0 | 2 | 1 | 0 | 2 |
X | Not in COG | 4 | 7 | 5 | 7 | 8 | 4 |
Total | 49 | 56 | 46 | 67 | 39 | 35 | |