Growth condition | IC50 (µM) | MIC (µM) | MBC (µM) |
---|
Planktonic growth | CPC: 0.6 | CPC: 1.2 | CPC: 2.5 |
CPB: 0.5 | CPB: 0.6 | CPB: 4.9 |
CPI: 0.7 | CPI: 1.2 | CPI: 4.9 |
Biofilm forming | CPC: 0.2 | CPC: 0.4 | CPC: 0.8 |
CPB: 0.2 | CPB: 0.4 | CPB: 0.8 |
CPI: 0.3 | CPI: 0.4 | CPI: 0.8 |
24 h biofilm | CPC: 24 | CPC: 43 | CPC: 172 |
CPB: 20 | CPB: 43 | CPB: 172 |
CPI: 32 | CPI: 86 | CPI: 172 |
- The antimicrobial activity of three halide salts of cetylpyridinium (CPC, CPB, and CPI) against S. mutans under different culture conditions (planktonic, biofilm forming, and 24 h biofilm) was measured by IC50, MIC, and MBC in a single experiment. For each condition, no significant effect was observed for the identity of the halide counter ion within the precision of these measurements