Skip to main content

Table 1 Top sense-strand sequence of NP and PA siRNAs, the location of the target sequence in the corresponding NP or PA virus gene and siRNA specificity with the original AIV gene

From: Inhibiting avian influenza virus shedding using a novel RNAi antiviral vector technology: proof of concept in an avian cell model

Gene (bp region) Sense strand sequence (5′–3′)
NP-siRNA GGA TCT TAT TTC TTC GGA G-dTdT
H8N4 NP (1486–1504) GGA TCT TAT TTC TTC GGA G
H6N2 NP (1453–1471) GGA TCT TAT TTC TTC GGA G
PA-siRNA GCA ATT GAG GAG TGC CTG A-dTdT
H8N4 PA (2077–2095) GCA ATT GAG GAG TGC CTG A
H6N2 PA (2065–2083) GCA ATT GAG GAG TGC CTG A