Table 6 Central composite design for the complex medium
Run | Coded factors | AMVL (mg/L) | ||||
|---|---|---|---|---|---|---|
A | B | C | D | Actual | Predicted | |
1 | −1 | −1 | −1 | −1 | 137.9 ± 5.3 | 129.1 |
2 | 1 | −1 | −1 | −1 | 134.5 ± 6.2 | 132.3 |
3 | −1 | 1 | −1 | −1 | 157.9 ± 7.1 | 152.1 |
4 | 1 | 1 | −1 | −1 | 183.0 ± 7.7 | 187.1 |
5 | −1 | −1 | 1 | −1 | 176.8 ± 8.4 | 175.9 |
6 | 1 | −1 | 1 | −1 | 184.9 ± 8.0 | 179.1 |
7 | −1 | 1 | 1 | −1 | 154.0 ± 6.5 | 151.2 |
8 | 1 | 1 | 1 | −1 | 189.8 ± 8.3 | 186.3 |
9 | −1 | −1 | −1 | 1 | 195.0 ± 8.6 | 187.4 |
10 | 1 | −1 | −1 | 1 | 165.8 ± 7.5 | 167.5 |
11 | −1 | 1 | −1 | 1 | 211.6 ± 9.7 | 210.3 |
12 | 1 | 1 | −1 | 1 | 224.1 ± 9.3 | 222.3 |
13 | −1 | −1 | 1 | 1 | 214.6 ± 9.1 | 209.5 |
14 | 1 | −1 | 1 | 1 | 194.9 ± 6.8 | 189.6 |
15 | −1 | 1 | 1 | 1 | 185.4 ± 5.7 | 184.8 |
16 | 1 | 1 | 1 | 1 | 195.2 ± 7.9 | 196.8 |
17 | −2 | 0 | 0 | 0 | 161.0 ± 7.6 | 172.1 |
18 | 2 | 0 | 0 | 0 | 187.2 ± 6.4 | 187.3 |
19 | 0 | −2 | 0 | 0 | 137.2 ± 4.1 | 148.7 |
20 | 0 | 2 | 0 | 0 | 179.2 ± 6.8 | 178.8 |
21 | 0 | 0 | −2 | 0 | 167.3 ± 6.7 | 172.6 |
22 | 0 | 0 | 2 | 0 | 188.1 ± 7.3 | 193.9 |
23 | 0 | 0 | 0 | −2 | 146.8 ± 5.2 | 154.2 |
24 | 0 | 0 | 0 | 2 | 219.2 ± 8.9 | 222.9 |
25 | 0 | 0 | 0 | 0 | 238.9 ± 9.5 | 242.2 |
26 | 0 | 0 | 0 | 0 | 248.8 ± 8.0 | 242.2 |
27 | 0 | 0 | 0 | 0 | 241.5 ± 8.2 | 242.2 |
28 | 0 | 0 | 0 | 0 | 243.3 ± 9.4 | 242.2 |
29 | 0 | 0 | 0 | 0 | 233.1 ± 6.7 | 242.2 |
30 | 0 | 0 | 0 | 0 | 247.5 ± 7.2 | 242.2 |