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Table 4 Statistical analysis of the Plackett-Burman design for the complex and defined media

From: Assessing medium constituents for optimal heterologous production of anhydromevalonolactone in recombinant Aspergillus oryzae

Variable Effect Coefficient p-value
Complex medium    
constant   65.04 < 0.0001
A, Sucrose 22.1004 11.05 0.0201
B, NaNO3 75.1828 37.59 < 0.0001
C, Yeast extract 30.4603 15.23 0.0025
D, KH2PO4 −4.7852 −2.39 0.5877
E, K2HPO4 27.8186 13.91 0.0049
F, KCl 8.7311 4.37 0.3272
G, MgSO4.7H2O 1.7222 0.86 0.8448
H, Trace elements −15.9140 −7.96 0.0830
Defined medium    
constant   42.14 < 0.0001
I, Sucrose 1.0233 0.51 0.7089
J, NaNO3 27.1197 13.56 < 0.0001
K, K2HPO4 −8.5673 −4.28 0.0052
L, KH2PO4 −10.8947 −5.45 0.0008
M, KCl −2.3609 −1.18 0.3930
N, MgSO4.7H2O 5.1297 2.56 0.0733
O, CaCl2.2H2O −5.7316 −2.87 0.0542
P, Na3C6H5O7.2H2O 2.7889 1.39 0.3149
Q, Biotin 1.1972 0.6 0.6625
R, Trace elements −22.8260 −11.41 < 0.0001