Fermentation performances of S. cerevisiae ISA1000, S288C and BY4741 strains in natural grape must (NGM). Open symbols indicate optical density for ISA1000 (▽), S288C (□) and BY4741 (◯ and red circle symbol) strains, respectively. Glucose consumption is represented by closed symbols. Glucose was completely consumed by ISA1000 and S288C strains (▼ and ■), in NGM; for BY4741 strain glucose was completely consumed in NGM (●), in NGM with auxotrophic supplements (1×) (blue circle symbol) and in NGM with auxotrophic supplements (2×) (red circle symbol). All fermentations were performed at 25°C. Representative results of one of three independent experiments are shown. OD, optical density.