Proposed pathway for CO
incorporation in C. cellulovorans . Possible metabolic maps of C. cellulovorans in media containing NaH13CO3
(a) and [U-13C]-glucose (b). Solid lines, possible pathways with directions indicated by arrows; dashed lines, impossible pathways in our studies. Lactate is produced from pyruvate, whereas fumarate is generated from oxaloacetate and malate. CO2 is fixed by PFOR and PEPC. In contrast, no citrate is produced from oxaloacetate.