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Table 4 MIC of cinnamaldehyde and eugenol against CA04 in the absence and presence of ergosterol

From: Phenyl aldehyde and propanoids exert multiple sites of action towards cell membrane and cell wall targeting ergosterol in Candida albicans

Test compounds

MIC (μg/mL)

-Ergosterol

+Ergosterol (100 μg/mL)

+Ergosterol (200 μg/mL)

Cinnamaldehyde

100

200

400

Eugenol

400

1600

1600

Amphotericin B (control)

1.0

2.0

4.0

  1. (−) absence of ergosterol.
  2. (+) presence of ergosterol.