Figure 6

Chitosan and benzoyl peroxide have additive antibacterial activity in combination. Chitosan was incubated with P. acnes in the presence or absence of benzoyl peroxide for 3 hours to assess antibacterial activity. Bacteria was then enumerated by colony-forming unit assay to determine concentration, which was plotted as a percentage of untreated sample. Error bars represent SEM (n = 3, independent experiments). *p < 0.05, **p < 0.01, and ***p < 0.001 (paired t-test).