Time courses of LiP and MnP activity levels in P. chrysosporium culture in the presence of various drugs. Each chemical was added after 48 h incubation. Effect on LiP activity (top panel) and MnP activity (bottom panel) under each condition. Error bars show the standard deviation (SD) for 3 biological repetitions. Mean values not sharing a common letter are significantly different between drug groups on the same day (P < 0.05), as estimated by Bonferroni method following 2-way repeated-measures ANOVA.