| IC50(mg/L) |
---|
Test substance | TNF-α | IL-6 |
---|
CEN1 HC-Br | ~4.0 | 0.0040 ± 0.053 |
CEN1 HC | 2.2 ± 0.4 | 0.33 ± 0.14 |
CEN1 HC (1–20) | 141.4 ± 18.4 | 9.8 ± 8.6 |
CEN1 HC (Ser) | 6.0 ± 2.4 | nd |
- Data are presented as half maximal inhibitory concentration (IC50) values ± SEM, as calculated by Origin software from dose–response curves using a 4-parameter fit. Due to an unsatisfactory curve fitting, IC50 for CEN1 HC-Br on TNF-α was estimated to approximately 4 mg/L. nd = not determined.