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Table 3 Analysis of Variance of quadratic model for bromelain production

From: Recombinant bromelain production in Escherichia coli: process optimization in shake flask culture by response surface methodology

Source Sum of squares F-value P-value
Model 30.67 99.32 0.0001
Post-induction temperature, A 1.22 35.71 0.0001
Inducer concentration, B 1.52 44.34 0.0001
Post-induction period, C 0.016 0.47 0.5102
A2 2.01 58.54 0.0001
B2 1.57 45.64 0.0001
C2 0.70 20.41 0.0001
AB 5.61 163.56 0.0001
AC 3.25 94.77 0.0001
BC 2.53 73.78 0.0001
Lack of fit 0.21 1.54 0.3233
  1. R2 = 0.9889, adjusted R2 = 0.9790, C.V. = 2.32, adequate precision = 31.695