Skip to main content

Table 1 Protein subfamilies of TAs according to Pfam; abbreviations: α-KG = α-ketoglutaric acid, PYR = pyruvate.

From: Transaminases for the synthesis of enantiopure beta-amino acids

protein sub-families

Pfam ID

folding type

members

amino donor

amino acceptor

EC

α-/ω-TAs

I and II

00155

I

aspartate TA

L-aspartate

α-KG

2.6.1.1

α

  

I

aromatic TA

L-phenylalanine

α-KG

2.6.1.57

α

III

00202

I

acetylornithine TA

acetylornithine

α-KG

2.6.1.11

ω

  

I

ornithine TA

ornithine

α-KG

2.6.1.13

ω

  

I

β-alanine:pyruvate TA

β-alanine

PYR

2.6.1.18

ω

  

I

β-TA from Mesorhizobium sp. LUK

β-phenylalanine

α-KG or PYR

n.c.1)

ω

  

I

4-aminobutyrate TA

4-aminobutyrate

α-KG

2.6.1.19

ω

IV

01063

IV

D-alanine TA

D-alanine

α-KG

2.6.1.21

α

  

IV

branched-chain amino-acid TA

leucine

α-KG

2.6.1.42

α

V

00266

I

phosphoserine TA

phosphoserine

α-KG

2.6.1.52

Α

VI

01041

I

ArnB

UDP-4-amino-4-deoxy-beta-L-arabinose

α-KG

2.6.1.87

α

  1. 1) n.c. = not classified