Figure 4From: SimReg1 is a master switch for biosynthesis and export of simocyclinone D8 and its precursorsInactivation of the simReg1 gene. (a) Schematic representation of the simReg1 gene disruption. (b) Results of the Southern hybridization of KpnI-digested plasmid pKCEsimR1 (1), BamHI digested total DNA samples from S. antibioticus ΔsimReg1 (2, 3) and Tü6040 (4) with 1.4 kb SmaI fragment harboring simReg1 gene.Back to article page