Skip to main content
AMB Express

Table 4 Pharmacokinetic (PK) profile of NFAT-133 (30 mg/kg) administered orally and intraperitoneally in female db/db mice

From: Fermentation, Isolation, Structure, and antidiabetic activity of NFAT-133 produced by Streptomyces strain PM0324667

PK

Oral

IP

T max (h)

0.08

0.08

C max (μg/ml)

3.41

11.653

C max (μM)

12.34

42.221

AUC last

0.63

3.217

AUC 0-infinity

0.65

3.553

T1/2 (h)

0.16

1.86

  1. IP: intraperitoneal, Tmax (h): Time to maximum observed plasma concentration, Cmax: Maximum observed plasma concentration, AUClast: Area under the concentration-time curve from time 0 to the time of last observed concentration, AUC0-infinity: Area under the concentration-time curve from time 0 to infinity, and T1/2: Terminal half-life.
Back to article page