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Table 1 Effect of different inhibitors on P. excavatus proteases.

From: Purification and characterization of novel fibrinolytic proteases as potential antithrombotic agents from earthworm Perionyx excavatus

Inhibitors Conc. (mM) Relative activity (%)
   FI FII FIII-1 FIII-2 FIII-3 FIV
Control   100 100 100 100 100 100
PMSF 1 0 0 2 4 0 8
TPCK 0.1 100 100 96 100 76 100
Aprotinin 0.01 29 95 87 95 26 71
Leupeptin 0.1 0 100 98 100 0 73
SBTI 0.01 0 76 81 93 0 0
EDTA 1 100 100 100 100 100 100
Chymostatin 0.1 19 100 76 100 19 90
Pepstatin 1 100 58 60 86 83 75
  1. Relative activity was determined as percentage of the activity of enzyme without inhibitor (control) (results were rounded up to the integer)