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Table 2 Sequence variations of CYP102A1 variantsa

From: Characterization of diverse natural variants of CYP102A1 found within a species of Bacillus megaterium

  CYP102A1 Variants  
  Mutated Amino acid Change of Nucleotide *2 *3 *4 *5 *6 *7 *8 *9 QMB1551
  T2P 4A > C          +
Heme domain V27I 79G > A +   +   + + + + +
  A29T 85G > A +   +   + + + + +
  V128I 382G > A +   + + + + + + +
  A136T 406G > A +   +   + + + + +
  E208D 624A > C     +      
  A222T 664G > A          +
  A296T 886G > A +   +       
  D370E 1110C > A +   +       
  K453Q 1357A > C     + + + + + +
  T464R 1392T > A     + + + + + +
  V471E 1413A > G     + + + + + +
Reductase domain K474T 1422G > C     + + + + + +
  A475V 1424C > T + + + + + + + + +
  Q513R 1539G > A       +    
  R526P 1578C > T      +     
  Q547E 1639C > G      + + + + +
  E559D 1677A > C + + +       
  L590F 1794C > A         +  
  A591S 1771G > T     +      
  D600E 1800C > A     + + + + + +
  V625L 1873G > T     + + + + + +
  D632N 1894G > A     +      
  D638E 1914T > A      + + + + +
  K640A 1920A > T     + + + + + +
  A652S 1954G > T          +
  G661R 1981G > C      + + + + +
  T665A 1993A > G + + + + + + + + +
  Q675K 2023C > A      + + + + +
  P676L 2027C > T + +        
  A679E 2036C > A + + +       
  E688A 2063A > C + + +       
  T716A 2146A > G      + + + + +
  A717T 2149G > A     + + + + + +
  A742G 2225C > G + + + + + + + + +
  A783V 2348C > T      + + + + +
  A796T 2386G > A     +      
  K814E 2440A > G + + + + + + + + +
  I825M 2474A > G     + + + + + +
  R826S 2476C > A + +        
  R837H 2510G > A + +        
  E871N 2613G > T + + +   + + + + +
  I882V 2644A > G + + + + + + + + +
  E888G 2663A > G + + + + + + + + +
  D894G 2681A > G      + + + + +
  P895S 2683C > T + + +       
  G913S 2739C > T    +       
  E948K 2842G > A      + + + + +
  S955N 2864G > A + + + + + + + + +
  M968V 2904G > A + + + + + + + + +
  Q971E 2911C > G      +     
  M980V 2938A > G     +      
  Q982R 2945A > G + +        
  A1009D 3026C > A + + + + + + + + +
  D1020E 3060C > A     + + + + + +
  H1022Y 3066C > T + + +       
  Q1023K 3067C > G     +      
  Q1023E 3067C > A + + +       
  G1040S 3118G > A     +      
  1. aVariations of amino acids and nucleotides in CYP102A1 variants (*2~*9) relative to CYP102A1.1 (P450 BM3) (*1) are shown by a (+) mark. Information regarding the CYP102A1 variant (designated as QMB1551) of B. megaterium QM B1551 (ATCC 12872) was obtained from the Whole Genome Sequencing of B. megaterium http://www.bios.niu.edu/b_megaterium/. We only used its genetic information to compare to those of other variants. Blanks mean no change of amino acids or nucleotides.